Repatha
Longest outcomes record in the class
Injection · Every 2 weeks or monthly
Lipid Management Program
Your heart health,
from every angle
Bring your numbers down and keep them there,
with testing, treatment, and a care team that work together.
Every driver, tested
60+ biomarkers, including ApoB, Lp(a), inflammation, and fasting insulin.
Every PCSK9 option
Injections and the first PCSK9 pill, plus statins when you need them.
Care that keeps adjusting
Retesting about 3 months after each change, with coaching in between.
$99/mo
Billed $297 every 3 months
Get started
Cancel anytime HSA/FSA eligible
- 60+ biomarkers, including ApoB & Lp(a)
- Advanced treatment options
- 1:1 longevity specialist care
- Retesting & treatment adjustments
We coordinate prescriptions and refills. Medication costs separate.
The science
Lower LDL today. Lower risk for years to come.
Decades of research show that lowering LDL earlier—and keeping it low—can reduce your risk of cardiovascular disease.
Lifelong LDL exposure
88%
Lower lifetime risk of heart attack in people born
with genes that keep LDL low.
Typical risk100%
Born with low LDL12%
Long-term benefit
25%
Lower risk of major cardiovascular events with Repatha after the first year, compared with 16% in year one.
First year16%
After year one25%
Why PCSK9 inhibitors?
The biggest advance in cholesterol treatment since statins
PCSK9 inhibitors work differently from statins, helping your body clear more LDL cholesterol from your blood.
Works alongside your statin
When statins aren’t enough, PCSK9 inhibitors can lower LDL another 50–60%.
An option beyond statins
They work differently and may be an option when statins aren’t suitable.
Lowers Lp(a) too
One of the few treatments that lower Lp(a), a largely genetic risk factor that diet and statins don’t fix.
Injection · Every 2 weeks or monthlyLipfendra
First oral PCSK9 inhibitor
Pill · Once dailyLerochol
Proven LDL-lowering efficacy
Injection · Once monthly
Could a PCSK9 inhibitor be right for you?
Your clinician will review your cardiovascular risk and determine whether treatment is appropriate.
- Relative risk reduction in the FOURIER key secondary composite endpoint (cardiovascular death, heart attack, or stroke).
- Up to about 8 years of follow-up in the FOURIER open-label extension; patients who started evolocumab earlier had fewer cardiovascular events over time.
- Percentage of evolocumab-treated patients showing coronary plaque regression in GLAGOV, compared with 47.3% receiving placebo. This represents the proportion of patients with regression, not the percentage of plaque removed.
Advanced testing
Heart disease has more than one driver.
We test all of them.
Normal LDL doesn't always mean low risk. Our 60+ biomarker panel covers every driver, and every result comes with a next step.
Cholesterol particles. ApoB and Lp(a) build plaque in your arteries. Lp(a) is mostly genetic, and few people get tested.
What we measure- ApoB
- Lp(a)
- LDL-C
What we do about itPCSK9 inhibitors, statins, ezetimibe, and nutrition, combined to reach your target.
Inflammation. Inflammation speeds up plaque buildup. hs-CRP shows how much is going on.
What we measure- hs-CRP
What we do about itCoaching on nutrition, training, and sleep, plus targeted supplements.
Metabolic health. Insulin resistance strains your arteries, and high blood sugar stiffens them over time.
What we measure- Fasting insulin
- Triglycerides
- HbA1c
- Glucose
What we do about itNutrition and training plans, plus GLP-1 medications when appropriate.
Your care team
Specialists who stay with you
Your care team sets personalized targets, tracks your progress, and adjusts your treatment over time.
- Clinicians
A plan that evolves with you
Your clinician sets personalized targets, reviews your results, and adjusts treatment as needed.
- Care team
Support that keeps you on track
Help with refills, treatment adjustments, and staying consistent with your care.
- Coaching
Support beyond medication
Guidance on nutrition, exercise, and lifestyle to support metabolic and cardiovascular health.
We don’t sell PCSK9 inhibitors or profit from prescriptions. We’re paid to manage your care, not to sell you medication.
Step 01
Measure
- Test the biomarkers that influence your cardiovascular health.
Step 02
Understand
- Review your results with your care team to identify what’s driving your risk.
Step 03
Prioritize
- Identify which risk factors matter most and where to focus your care.
Step 04
Treat
- Get a personalized treatment plan, including medication when appropriate.
Step 05
Remeasure
- Track your progress with follow-up testing and adjust your care over time.
Lipid Management Program
Advanced testing, a clinician, coaching, and retesting, all in one program.
$99/ month
Billed $297 every 3 months
- 60+Biomarkers
- ~3 moRetest after changes
- 3PCSK9 options
Membership includes
- 60+ biomarker testing
- A clinician who sets your targets
- Coaching between labs
- Retesting as your plan changes
- Clinician review for PCSK9 inhibitors
- 20% off statins and ezetimibe
- Medications billed separately
Medications and cost
Your clinician prescribes it. Your pharmacy fills it.
Medications aren’t included in membership and are billed separately. If treatment is right for you, here’s how you’d get it.
Healthspan doesn’t sell or ship PCSK9 inhibitors, and they’re available to members only. Statins are filled through our pharmacy partner, 20% off for members. Ezetimibe is also available. A clinician decides every prescription, so a prescription isn’t guaranteed.
The Healthspan difference
More than a prescription. A complete approach to heart health.
Advanced testing, modern treatments, and ongoing care, all working together.
- 01TestingTraditional care
Testing that stops at LDL.
What we do insteadWe measure lipids, inflammation, and metabolic health.
- 02TreatmentTraditional care
Treatment that stops at a statin.
What we do insteadWe help you access advanced cholesterol-lowering treatments when clinically appropriate.
- 03Ongoing careTraditional care
Care that stops after the first prescription.
What we do insteadYour care team keeps monitoring, retesting, and adjusting your treatment over time.
How low you bring your cholesterol matters. How long you keep it there matters just as much.
Get started
Questions, answered.
A cholesterol-lowering medication that blocks a protein called PCSK9. With less PCSK9, your liver keeps more of the receptors that clear LDL ("bad") cholesterol from your blood. It's available as an injection (Repatha, Lerochol) or a once-daily pill (Lipfendra).
Usually not. PCSK9 inhibitors are often added to a statin to lower LDL further, and they can be used on their own if statins don't agree with you. Don't stop or change any medication without talking to your clinician first.
Only if it's clinically appropriate. Your clinician reviews your history, lab results, and current medications before prescribing anything, so a prescription isn't guaranteed. You're welcome to share your preferences, and your clinician weighs them alongside your results, risk, and goals.
Your membership covers biomarker testing, your clinical team, ongoing guidance, and follow-up retesting. Medications aren't included and are billed separately.
Healthspan doesn't sell or ship PCSK9 inhibitors. If one is right for you, your clinician sends the prescription to your local pharmacy, where insurance may apply, or to the manufacturer's program for Lerochol ($199/month). Statins and ezetimibe can be filled through our pharmacy partner.
You'll retest after each treatment change and review the results with your clinician. Your plan is adjusted over time based on how your numbers respond.
Possibly. A normal LDL doesn't always mean low risk: ApoB, Lp(a), inflammation, and metabolic health can tell a different story. Testing helps you and your clinician see the full picture.