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Suppressing Two Signals of Aging: Insights from the 2025 Rapamycin–Trametinib Study
Targeting mTOR with Rapamycin Across Species: How Hypertrophic Cardiomyopathy Reversal in Cats Informs Human Cardiac Aging and Longevity
The Biology of Cold Exposure: A Hormetic Stressor That Activates Autophagy, Improves Metabolism, and Reduces Inflammation—But Only If You Shiver
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All studies
(rapamycin)
Longevity
07 / 19 / 2025
•
16 MIN READ
Suppressing Two Signals of Aging: Insights from the 2025 Rapamycin–Trametinib Study
Longevity
07 / 11 / 2025
•
19 MIN READ
Targeting mTOR with Rapamycin Across Species: How Hypertrophic Cardiomyopathy Reversal in Cats Informs Human Cardiac Aging and Longevity
Longevity
06 / 21 / 2025
•
29 MIN READ
The Case for Cyclical Longevity Protocols: How Rhythmic Activation of AMPK and Autophagy Reprograms Aging Cells
Longevity
05 / 30 / 2025
•
32 MIN READ
The Mitochondrial Signature of Long COVID: What PRDX3 Is Trying to Tell Us—And How We Might Reverse It
Brain
05 / 17 / 2025
•
16 MIN READ
Rewiring the Brain’s Fullness Signal: Rapamycin’s Role in Leptin Sensitivity
Metabolism
01 / 25 / 2025
•
21 MIN READ
Mitochondria’s Paradoxical Role in Cancer Biology: Exploiting Metabolic Vulnerabilities for Therapeutic Targeting
Longevity
01 / 11 / 2025
•
38 MIN READ
Connecting mTOR and Mitochondria: The Novel Synergy Between Rapamycin and Urolithin A
Longevity
12 / 07 / 2024
•
25 MIN READ
Two Waves of Aging: How Midlife Biomolecular Shifts Accelerate Decline
Brain
11 / 23 / 2024
•
25 MIN READ
The Surprising Role of Rapamycin in Treating Long COVID and Post-Viral Syndromes
Longevity
10 / 12 / 2024
•
25 MIN READ
Targeting Inflammation and Bone Loss in Periodontal Disease with Low-Dose Rapamycin: A Review of Mechanisms and Clinical Potential
Longevity
10 / 04 / 2024
•
7 MIN READ
Research Review: PEARL Study on Rapamycin for Age-Related Healthspan Improvements
Metabolism
06 / 29 / 2024
•
33 MIN READ
Optimizing Longevity Protocols: The Synergistic Potential of Rapamycin, Acarbose, and Metformin
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