Treatments
Personalized Protocols
Labs
Medications
Supplements
Optimization
Labs
Coaching
Personalized Protocols
Goals
Optimize longevity
Fat loss
Target joint pain
Grow stronger, healthier hair
Boost energy
Get healthier skin
About
Our Company
Our Mission
How it Works
Read our latest research
Suppressing Two Signals of Aging: Insights from the 2025 Rapamycin–Trametinib Study
Targeting mTOR with Rapamycin Across Species: How Hypertrophic Cardiomyopathy Reversal in Cats Informs Human Cardiac Aging and Longevity
The Biology of Cold Exposure: A Hormetic Stressor That Activates Autophagy, Improves Metabolism, and Reduces Inflammation—But Only If You Shiver
Research
Log in
Get Started
Menu
Treatments
Optimization
Goals
About
Research
Log in
Get started
All studies
(mitochondrial health)
Longevity
07 / 04 / 2025
•
11 MIN READ
The Biology of Cold Exposure: A Hormetic Stressor That Activates Autophagy, Improves Metabolism, and Reduces Inflammation—But Only If You Shiver
Brain
06 / 07 / 2025
•
20 MIN READ
The Energy Equation in Alzheimer’s Disease: Glucose-Driven Degeneration and Ketone-Driven Protection
Longevity
05 / 30 / 2025
•
32 MIN READ
The Mitochondrial Signature of Long COVID: What PRDX3 Is Trying to Tell Us—And How We Might Reverse It
Lifestyle
05 / 24 / 2025
•
20 MIN READ
The Molecular Effects of Resistance Training on Aging Muscle and Senescent Cell Burden
Brain
05 / 03 / 2025
•
34 MIN READ
Methylene Blue for the Aging Brain: Mitochondrial Mechanisms Driving Neuroprotective and Cognitive Benefits
Metabolism
04 / 26 / 2025
•
14 MIN READ
Pharmacological Fasting: How SGLT-2 Inhibitors Emulate Caloric Restriction to Target Key Longevity Pathways
Metabolism
04 / 05 / 2025
•
23 MIN READ
Beyond Plaques: How Methylene Blue and Ketones Address Vascular-Hypometabolism in Alzheimer’s Disease
Metabolism
03 / 15 / 2025
•
17 MIN READ
Harnessing Chronobiology for Metabolic Health: The Role of Brown Fat and Circadian Rhythms
Metabolism
03 / 08 / 2025
•
28 MIN READ
SGLT2 Inhibitors as Metabolic Senolytics: Clearing Senescent Cells to Combat Pathological Aging
Metabolism
02 / 28 / 2025
•
23 MIN READ
Reevaluating Midlife Metabolic Decline: A Four-Factor Framework Integrating Muscle, Mitochondrial Function, Hormones, and Inflammation
Metabolism
02 / 01 / 2025
•
13 MIN READ
Emergence of Specialized Mitochondrial Networks: A ‘Divide and Conquer’ Strategy for Metabolic Demands
Metabolism
01 / 25 / 2025
•
21 MIN READ
Mitochondria’s Paradoxical Role in Cancer Biology: Exploiting Metabolic Vulnerabilities for Therapeutic Targeting
show more
mitochondrial health | Healthspan