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Suppressing Two Signals of Aging: Insights from the 2025 Rapamycin–Trametinib Study
Targeting mTOR with Rapamycin Across Species: How Hypertrophic Cardiomyopathy Reversal in Cats Informs Human Cardiac Aging and Longevity
The Biology of Cold Exposure: A Hormetic Stressor That Activates Autophagy, Improves Metabolism, and Reduces Inflammation—But Only If You Shiver
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All studies
(mTOR)
Longevity
06 / 21 / 2025
•
29 MIN READ
The Case for Cyclical Longevity Protocols: How Rhythmic Activation of AMPK and Autophagy Reprograms Aging Cells
Metabolism
04 / 26 / 2025
•
14 MIN READ
Pharmacological Fasting: How SGLT-2 Inhibitors Emulate Caloric Restriction to Target Key Longevity Pathways
Longevity
11 / 16 / 2024
•
41 MIN READ
The Science of Mitophagy: Urolithin A’s Impact on Mitochondrial Function and Aging
Longevity
07 / 13 / 2024
•
26 MIN READ
The Paradox of Iron and Aging: Exploring Iron Overload's Role in Aging and the Therapeutic Benefits of Blood Donation
Metabolism
06 / 29 / 2024
•
33 MIN READ
Optimizing Longevity Protocols: The Synergistic Potential of Rapamycin, Acarbose, and Metformin
Longevity
06 / 22 / 2024
•
35 MIN READ
Regulating Anabolic and Catabolic Signaling for Healthspan Optimization: Impacts of Rapamycin, Exercise, and Testosterone Replacement Therapy
Longevity
04 / 27 / 2024
•
18 MIN READ
Iron Overload and Cellular Aging: The Critical Interplay Between Iron and Copper in mTOR Signaling and Oxidative Stress
Longevity
03 / 23 / 2024
•
29 MIN READ
Autophagy, Cellular Senescence, and the Promise of Topical Rapamycin in Hair Regeneration
Longevity
11 / 16 / 2023
•
11 MIN READ
Taming Aging With Metformin: How A Diabetes Medication Can Change The Way We Age
Brain
11 / 03 / 2023
•
11 MIN READ
Examining mTOR's Influence on Multiple Sclerosis: A Scientific Review of Rapamycin's Therapeutic Potential