My experience with Healthspan has been pivotal because everyone listens and wants to help…and being on HRT has changed my life.
Estradiol Patch
Estradiol patches deliver bioidentical estrogen through the skin to relieve menopausal symptoms. HRT medications are accessed through Membership, which includes labs and ongoing clinical care for safe prescribing and treatment.
Helps stabilize temperature regulation and improve sleep quality by restoring consistent estrogen signaling.
Helps preserve bone density while supporting cognitive and cardiovascular health over time.
Provides continuous estrogen delivery through the skin, reducing daily hormone fluctuations.
benefits
Your symptoms start with biology. So does relief.
Restores estrogen signaling involved in temperature regulation and sleep
Supports brain and nervous system function tied to mood and cognition
Preserves bone remodeling and connective tissue health
your complete care
Personalized HRT care starts with membership
Your health is personal, and so is our approach. We use the latest science and data-driven insights to design care built around you.
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We pioneered modern longevity care, making it accessible to all.
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Effective treatments and excellent service earns us loyal support.
20
+
avg. yrs of experience
The MDs and PhDs on our clinical and research teams are experts.
70
K
biomarkers analyzed
Our team uses lab data to personalize care and track progress.
Patient Spotlight
Real women. Real stories.
Clinician-guided HRT treatment
Clinician-guided bioidentical HRT for symptom relief and long-term health.
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Frequently asked questions
An estradiol patch is a prescription hormone therapy that delivers bioidentical estradiol (E2) through the skin. Estradiol is the primary and most biologically active form of estrogen in the body and plays a key role in temperature regulation, bone health, brain function, and cardiovascular health.
The patch delivers estradiol steadily through the skin, allowing it to enter the bloodstream directly. This avoids first-pass metabolism through the liver and provides more consistent estrogen levels compared to oral estrogen, which may improve tolerability for many women.
Some women notice early improvement in hot flashes, night sweats, or sleep within 1–2 weeks. More consistent symptom relief often develops over 6–12 weeks, while benefits related to bone, skin, and connective tissue develop gradually over several months.
Estradiol therapy is commonly used to relieve menopausal and perimenopausal symptoms such as: hot flashes and night sweats; sleep disruption; mood changes and cognitive symptoms; and vaginal and urinary discomfort. It also supports long-term bone, brain, and cardiovascular health when prescribed appropriately.
Estradiol therapy is considered safe for many women when prescribed and monitored by a qualified clinician. Transdermal estrogen is associated with a lower risk of blood clots compared to oral estrogen for many patients. Your care team evaluates your medical history, symptoms, and labs to determine whether therapy is appropriate and adjusts treatment over time.
Common side effects may include breast tenderness, mild spotting (especially early in treatment), headache, or nausea. Some women experience mild skin irritation at the application site, which can often be reduced by rotating patch placement. Your clinician will review potential side effects and monitor your response over time.
The estradiol patch requires ongoing clinical oversight to be prescribed safely and effectively. At Healthspan, HRT medications are delivered through membership because hormone levels, symptoms, and side effects change over time and need active monitoring. Membership includes baseline and follow-up lab testing, clinician review, and ongoing support to ensure dosing remains within safe ranges, treatment stays effective, and potential risks are identified early. This care model is designed to support long-term health outcomes, not one-time prescribing.
Estradiol patch therapy through Healthspan includes two components: membership and medication. The estradiol patch is priced at $140 per month, and Healthspan members receive a discounted rate of $112 per month. When billed quarterly, the cost is $336, marked down from $420. Membership covers the clinical care required for safe and effective treatment, including lab testing, clinician review, and ongoing support. Medication is billed separately and only when prescribed.
An estradiol patch is a prescription hormone therapy that delivers bioidentical estradiol (E2) through the skin. Estradiol is the primary and most biologically active form of estrogen in the body and plays a key role in temperature regulation, bone health, brain function, and cardiovascular health.
The patch delivers estradiol steadily through the skin, allowing it to enter the bloodstream directly. This avoids first-pass metabolism through the liver and provides more consistent estrogen levels compared to oral estrogen, which may improve tolerability for many women.
Some women notice early improvement in hot flashes, night sweats, or sleep within 1–2 weeks. More consistent symptom relief often develops over 6–12 weeks, while benefits related to bone, skin, and connective tissue develop gradually over several months.
Estradiol therapy is commonly used to relieve menopausal and perimenopausal symptoms such as: hot flashes and night sweats; sleep disruption; mood changes and cognitive symptoms; and vaginal and urinary discomfort. It also supports long-term bone, brain, and cardiovascular health when prescribed appropriately.
Estradiol therapy is considered safe for many women when prescribed and monitored by a qualified clinician. Transdermal estrogen is associated with a lower risk of blood clots compared to oral estrogen for many patients. Your care team evaluates your medical history, symptoms, and labs to determine whether therapy is appropriate and adjusts treatment over time.
Common side effects may include breast tenderness, mild spotting (especially early in treatment), headache, or nausea. Some women experience mild skin irritation at the application site, which can often be reduced by rotating patch placement. Your clinician will review potential side effects and monitor your response over time.
The estradiol patch requires ongoing clinical oversight to be prescribed safely and effectively. At Healthspan, HRT medications are delivered through membership because hormone levels, symptoms, and side effects change over time and need active monitoring. Membership includes baseline and follow-up lab testing, clinician review, and ongoing support to ensure dosing remains within safe ranges, treatment stays effective, and potential risks are identified early. This care model is designed to support long-term health outcomes, not one-time prescribing.
Estradiol patch therapy through Healthspan includes two components: membership and medication. The estradiol patch is priced at $140 per month, and Healthspan members receive a discounted rate of $112 per month. When billed quarterly, the cost is $336, marked down from $420. Membership covers the clinical care required for safe and effective treatment, including lab testing, clinician review, and ongoing support. Medication is billed separately and only when prescribed.
