I've been on your therapy for 8 months and it's been life-changing.
Zepbound® with Ongoing Care
A dual-pathway GLP-1/GIP injectable with the most potent metabolic and weight-loss benefits. Prescribed through a Healthspan Membership with clinician-led evaluation and ongoing care to manage dosing, labs, and long-term health.
Your provider will review your medical history and goals to determine eligibility. If prescribed, medication is billed separately and fulfilled through LillyDirect.
Your care team manages dosing and tolerance, reviews labs, and provides guidance on nutrition and strength to support safe, sustainable progress.
Regular check-ins and labs track 70+ biomarkers beyond weight, including metabolic health, body composition, lean muscle, and sleep.
Up to 20% body weight reduction with Zepbound
As a dual GLP-1/GIP agonist, Zepbound offers the highest weight-loss potential seen with GLP-1 therapy. Expert support helps patients maximize and sustain results over time.
Why ongoing care keeps GLP-1 therapy safe, durable, and effective
2x
Longer on therapy
Ongoing support keeps patients on GLP-1s 2x longer, maximizing long-term benefits
9+
Systems affected
GLP-1s influence brain, heart, kidney, & more. Tracking biomarkers across these systems enables better care
85%+
Muscle mass preserved
With guidance, patients preserve lean muscle through targeted protein and strength protocols
0-6 mo.
Critical adjustment period
Early months require guidance for dosing, tolerance, & progress for long-term success
Most GLP-1 programs stop at the prescription
Ours starts there
your complete care
Your personalized GLP-1 care starts with membership
Clinician-guided GLP-1 treatment
Your clinician reviews your medical history and goals to determine eligibility and guide the right treatment choice, including injectable or oral options.
Supporting brain function
GLP-1s cross the blood–brain barrier and have been studied for effects on neuroinflammation, mood regulation, and cognitive resilience, with early evidence suggesting neuroprotective potential.
Protecting cardiovascular health
Large outcome trials show reductions in major adverse cardiac events, linked to improved endothelial function, lower inflammation, and favorable lipid and blood pressure changes.
Supporting kidney function
GLP-1s have been associated with reduced albuminuria and slower progression of diabetic kidney disease in some populations.
Improving liver health
GLP-1s are well studied in NAFLD and NASH, with evidence showing reductions in liver fat and improvements in insulin sensitivity and liver enzymes.
Supporting PCOS & fertility
GLP-1 therapy has been associated with improvements in insulin resistance, ovulatory function, and androgen levels in individuals with PCOS, with emerging evidence for fertility benefits.
Reducing chronic inflammation
GLP-1 signaling has been linked to lower systemic inflammation, including reductions in CRP and improvements in endothelial and neuroinflammatory markers.
Improving body composition
GLP-1s influence fat loss and visceral fat reduction while impacting appetite regulation and metabolic efficiency; preserving lean mass remains a key clinical consideration.
Supporting respiratory health
Tirzepatide has been studied for weight-related obstructive sleep apnea, showing clinically meaningful reductions in apnea–hypopnea index.
Hear from our patients
Frequently asked questions
In clinical trials, patients lost an average of 20% of their body weight when Zepbound was paired with lifestyle changes. Without those changes, real-world results are closer to 10–15%. Even at that level, Zepbound delivers more weight loss than any other GLP-1 medication — and with Healthspan’s coaching to support healthy habits, you can work toward the higher results seen in trials.
Zepbound is the first dual-agonist medication. It activates GLP-1 and GIP pathways to slow digestion, reduce appetite and food cravings, and improve blood sugar balance.
Yes. Through your Healthspan membership, you’ll get safe access to FDA-approved Zepbound, along with labs, clinician oversight, and coaching to help sustain results.
Many patients notice changes within the first few weeks, though results build over months. Your clinician will monitor progress and adjust dosing as needed.
The GLP-1 membership is designed to support GLP-1 therapy as ongoing medical care, not a one-time prescription. Membership includes clinician evaluation and prescribing, personalized dosing and titration over time, and continued clinical oversight as your body responds to treatment. Members also receive support for side-effect management, nutrition as appetite changes, and muscle-preservation strategies to support long-term metabolic health. The membership includes ongoing biomarker and lifestyle tracking, with labs incorporated into care when clinically appropriate to monitor metabolic health and guide treatment decisions over time. Labs are not required to start treatment, but are an important part of Healthspan’s longevity-focused approach as therapy progresses. Membership starts at $99 per month. GLP-1 medications are billed separately based on the prescription and pharmacy used. As part of the membership, Healthspan helps coordinate prescriptions, refills, and medication logistics as treatment evolves.
Like other GLP-1 medications, Zepbound can cause nausea, vomiting, or digestive changes. Our clinicians help manage dosing and side effects for safety and comfort.
GLP-1s can lead to loss of lean muscle if not managed properly. At Healthspan, we integrate labs, coaching, and nutrition strategies to prioritize muscle retention - protecting long-term strength, mobility, and healthspan.
Yes, many patients are able to use HSA or FSA dollars for their Healthspan membership, depending on individual account rules.
LillyDirect is Eli Lilly’s direct-to-consumer website that helps patients quickly access Lilly’s medicines, managing prescriptions, payment, and shipping all in one place. It removes middlemen to provide direct access to authentic, FDA-approved GLP-1 medications especially valuable for those who may not be insured. We offer this option to ensure the highest standards of quality and purity, while making care more convenient, affordable, and accessible.
In clinical trials, patients lost an average of 20% of their body weight when Zepbound was paired with lifestyle changes. Without those changes, real-world results are closer to 10–15%. Even at that level, Zepbound delivers more weight loss than any other GLP-1 medication — and with Healthspan’s coaching to support healthy habits, you can work toward the higher results seen in trials.
Zepbound is the first dual-agonist medication. It activates GLP-1 and GIP pathways to slow digestion, reduce appetite and food cravings, and improve blood sugar balance.
Yes. Through your Healthspan membership, you’ll get safe access to FDA-approved Zepbound, along with labs, clinician oversight, and coaching to help sustain results.
Many patients notice changes within the first few weeks, though results build over months. Your clinician will monitor progress and adjust dosing as needed.
The GLP-1 membership is designed to support GLP-1 therapy as ongoing medical care, not a one-time prescription. Membership includes clinician evaluation and prescribing, personalized dosing and titration over time, and continued clinical oversight as your body responds to treatment. Members also receive support for side-effect management, nutrition as appetite changes, and muscle-preservation strategies to support long-term metabolic health. The membership includes ongoing biomarker and lifestyle tracking, with labs incorporated into care when clinically appropriate to monitor metabolic health and guide treatment decisions over time. Labs are not required to start treatment, but are an important part of Healthspan’s longevity-focused approach as therapy progresses. Membership starts at $99 per month. GLP-1 medications are billed separately based on the prescription and pharmacy used. As part of the membership, Healthspan helps coordinate prescriptions, refills, and medication logistics as treatment evolves.
Like other GLP-1 medications, Zepbound can cause nausea, vomiting, or digestive changes. Our clinicians help manage dosing and side effects for safety and comfort.
GLP-1s can lead to loss of lean muscle if not managed properly. At Healthspan, we integrate labs, coaching, and nutrition strategies to prioritize muscle retention - protecting long-term strength, mobility, and healthspan.
Yes, many patients are able to use HSA or FSA dollars for their Healthspan membership, depending on individual account rules.
LillyDirect is Eli Lilly’s direct-to-consumer website that helps patients quickly access Lilly’s medicines, managing prescriptions, payment, and shipping all in one place. It removes middlemen to provide direct access to authentic, FDA-approved GLP-1 medications especially valuable for those who may not be insured. We offer this option to ensure the highest standards of quality and purity, while making care more convenient, affordable, and accessible.
