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Suppressing Two Signals of Aging: Insights from the 2025 Rapamycin–Trametinib Study
Targeting mTOR with Rapamycin Across Species: How Hypertrophic Cardiomyopathy Reversal in Cats Informs Human Cardiac Aging and Longevity
The Biology of Cold Exposure: A Hormetic Stressor That Activates Autophagy, Improves Metabolism, and Reduces Inflammation—But Only If You Shiver
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All studies
(Aging)
Longevity
06 / 21 / 2025
•
29 MIN READ
The Case for Cyclical Longevity Protocols: How Rhythmic Activation of AMPK and Autophagy Reprograms Aging Cells
Longevity
06 / 13 / 2025
•
14 MIN READ
How Stress Alters DNA Methylation to Accelerate Biological Age — and How Oxytocin May Modulate This Epigenetic Pathway
Metabolism
04 / 26 / 2025
•
14 MIN READ
Pharmacological Fasting: How SGLT-2 Inhibitors Emulate Caloric Restriction to Target Key Longevity Pathways
Metabolism
03 / 08 / 2025
•
28 MIN READ
SGLT2 Inhibitors as Metabolic Senolytics: Clearing Senescent Cells to Combat Pathological Aging
Metabolism
01 / 18 / 2025
•
28 MIN READ
SGLT-2 Inhibitors in Aging and Healthspan: Surprising Mechanistic Insights Into Adipose Tissue Reduction, Lean Mass Preservation, and Longevity
Metabolism
09 / 06 / 2024
•
14 MIN READ
Acarbose’s Impact on Glucose Metabolism, Gut Health, and Inflammation: The Potential in Colorectal Cancer Prevention
Longevity
06 / 08 / 2024
•
33 MIN READ
Resveratrol and Aging: A Comprehensive Review of Longevity Claims and Scientific Findings
Longevity
04 / 27 / 2024
•
18 MIN READ
Iron Overload and Cellular Aging: The Critical Interplay Between Iron and Copper in mTOR Signaling and Oxidative Stress
Longevity
04 / 13 / 2024
•
16 MIN READ
Understanding Aging Through Advanced Biomarkers: A Detailed Overview
Longevity
03 / 23 / 2024
•
29 MIN READ
Autophagy, Cellular Senescence, and the Promise of Topical Rapamycin in Hair Regeneration
Longevity
03 / 16 / 2024
•
16 MIN READ
Nature's Design Paradox: Aging as an Inherent Software Flaw
Metabolism
02 / 10 / 2024
•
6 MIN READ
From Glucose Control to Gut Health: How Acarbose Bridges Metabolic Disease Management, Microbiome Science, and Aging Processes
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Aging | Healthspan